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Amged A. Ouf

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Aug 2026

Siwa spring microbiomes as reservoirs of biosynthetic gene clusters: Unlocking natural product potential

The integrated bioinformatics pipeline enabled the reconstruction of 37 medium-to-high-quality metagenome-assembled genomes (MAGs), and recovered 147 BGCs mostly from Pseudomonadota, Actinomycetota, and Acidobacteriota phyla, highlighting the Siwa Oasis as a promising reservoir of unexplored biosynthetic potential and a valuable resource for natural product discovery to address global health challenges.

Muhammad A. Ajagbe, Shimaa F Ahmed, Amged A. Ouf et al. · 0 citations