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Review Open access Sep 2026

Gene—diet interactions in cardiovascular disease: insights from nutrigenetics, nutrigenomics, and precision nutrition

Cardiovascular disease (CVD) remains the leading global cause of mortality, with diet as a major modifiable determinant of risk. However, substantial interindividual variability in lipid, glycemic, inflammatory, and blood pressure responses to dietary interventions suggests that uniform dietary recommendations may not...

M. Ramadan, Amie Jobe, Ranjit Vijayan · 0 citations
Aug 2026

Molecular basis of angiotensin-converting enzyme 1 selectivity of food-derived anti-hypertensive peptides.

Angiotensin converting enzyme 1 (ACE1) is a key regulator of the renin-angiotensin system. Given that the catalytic domains of the ACE homologs are highly similar, ACE1 inhibitory peptides may inadvertently interfere with ACE2, potentially disrupting RAS homeostasis. Here, we investigated the molecular basis of ACE1/AC...

Amie Jobe, Jaleel Kizhakkayil, Y. Al Dhaheri et al. · 0 citations

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