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Author

Amina Tariq

1 paper indexed here

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Sep 2026

Functional group-dependent stabilization and dissociation mechanisms of EGFR allosteric inhibitors.

Allosteric inhibitors targeting the αC-helix-adjacent pocket provide an alternative strategy to overcome resistance associated with ATP-site mutations. However, the structural and thermodynamic determinants governing their stability across resistant EGFR variants remain incompletely understood. Here, we comparatively i...

Amina Tariq, M. Shoaib, Ling-Bo Qu et al. · 0 citations

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