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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Amirabas Bostani

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Open access Jan 2026

Naringenin Attenuates Diabetic Cardiac Injury via SIRT1 Activation in Streptozotocin‐Induced Rats

Objective Diabetic cardiomyopathy (DCM) lacks targeted therapies. This study investigated naringenin (NAR), a citrus flavonoid, in a streptozotocin (STZ)‐induced diabetic rat model with cardiac complications, focusing on SIRT1‐mediated mechanisms. Methods Rats (n = 8/group) included control, NAR, DCM, DCM + NAR, and DC...

Bao-Lan Wang, Dan-Dan Zhang, Fu-Dan Zhang et al. · 0 citations
Open access Sep 2026

Baicalein Attenuates Early Molecular and Proliferative Changes in MASH-Driven Hepatocarcinogenesis by Inhibiting the NLRP3 Inflammasome and Pyroptosis Pathway

Background Metabolic dysfunction-associated steatohepatitis (MASH) is a major risk factor for hepatocellular carcinoma (HCC). The nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome and pyroptosis are key drivers of inflammation and tumorigenesis. Baicalein (BAI...

Jing Xu, Amirabas Bostani, Hong-Wei Qu · 0 citations
Open access Sep 2026

Ellagic Acid Enhances RSL3‐Induced Ferroptosis by Inhibiting the Nrf2/HO‐1 Signaling Pathway in Pancreatic Ductal Adenocarcinoma

EA potentiates RSL3‐induced ferroptosis in PDAC by disrupting the p38/Nrf2/HO‐1 axis and elevating Keap1, a natural compound‐based strategy overcomes redox‐driven resistance, offering a translatable approach for PDAC models.

Jian-Hua Bai, Yi-He Dai, Chern Ein Oon et al. · 0 citations

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