Open access
Sep 2026
Top-Down Proteomics in the Assessment of Kidney Donor Quality: a proof-of-concept for increased organ utilization.
A persistent barrier to optimizing the utilization of deceased donor kidneys, nearly 30% of which are discarded, is the absence of objective, molecularly resolved metrics of organ quality. To address this gap, we integrated high-resolution proteoform imaging mass spectrometry (PiMS) of donor kidney biopsies with deep L...
C. Ctortecka, D. Jaishankar, Pei-Chia Su et al.
· Molecular & Cellular Proteom... · 0 citations