Amr Elagamy

Discovery of chromone-derived EGFR inhibitors as potent apoptosis inducers in cancer: In vitro and in vivo insights.

Compound 4v emerged as a leading candidate, showing EGFR kinase inhibitory activity comparable to Erlotinib, and computational analysis of 4v and EGFR molecular binding suggests that it serves as a superior binder to the inactive EGFR conformation.