Tissue-resident memory T cells in autoimmune chronicity and relapse: mechanisms and therapeutic implications.
Tissue-resident memory T (Trm) cells are a specialized subset of memory T cells that persist in peripheral tissues (skin, joints, intestine) without recirculating, serving as a frontline defense against pathogen reinfection. This protective function is exemplified by interleukin-15 (IL-15), C-X-C chemokine receptor typ...