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Author

Ana Paula de Sousa Mesquita

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Open access Aug 2026

PIK3CA silencing restores anoikis sensitivity in endothelial cells

The development, differentiation, and homeostasis of adherent cells are regulated by interactions among cells, the extracellular matrix (ECM), and soluble factors. Loss of these contacts induces anoikis, a specific form of apoptosis. Tumor cells acquire resistance to anoikis, enabling them to survive without anchorage,...

Diego Mauro Carneiro Pereira, Ana Paula de Sousa Mesquita, Amanda da Silva Cruz et al. · 0 citations

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