Andrada-Nicole Georgescu

Spatiotemporal characterization of corticolimbic dopamine and noradrenaline signaling and affective state modulation by mfb stimulation

Background Deep brain stimulation of the medial forebrain bundle (mfb-DBS) is a promising intervention for psychiatric disorders, but the neurochemical mechanisms underlying its effects remain incompletely understood. Methods In adult Sprague–Dawley rats, fiber photometry was used to monitor mfb-DBS evoked dopamine (DA...