Review
Open access
Oct 2026
Hepatitis E virus genome plasticity: a marker of chronicity and therapy failure?
Hepatitis E virus (HEV) is a globally distributed zoonotic pathogen, spread by contaminated food and blood products, and a leading cause of acute viral hepatitis. Recent data indicate that the HEV genome contains a highly heterogeneous hypervariable region (HVR) that can tolerate extensive genomic rearrangements, espec...
Saskia Janshoff, Leyla Sirkinti, M. Nocke et al.
· Communications Biology · 0 citations