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Author

Andrea Angarita-Rodríguez

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Review Open access Sep 2026

Gut microbiota signatures in mild cognitive impairment: a scoping review of microbial taxa and clinical implications

Objective To identify systematically the typical gut microbiota in mild cognitive impairment patients and its association in disease progression. Systematically identify microbial taxa consistently associated with Mild Cognitive Impairment. Design A scoping review was performed according to the guidelines of the Joanna...

Óscar Gabriel Beltrán, Andrea Angarita-Rodríguez, Janneth González et al. · 0 citations
Open access Sep 2026

Integrative genome-scale metabolic model of GABAergic neurons reveals metabolic signatures across the mild cognitive impairment – Alzheimer disease continuum

This work provides a systems-level computational framework linking transcriptomic alterations with predicted metabolic remodeling in GABAergic neurons and generates experimentally testable hypotheses regarding metabolic dysfunction during progression from MCI to AD.

Andrea Angarita-Rodríguez, Johan H. Largo-González, Julián Pérez-Mejía et al. · 0 citations
Open access Jul 2026

Comparative evaluation of reference-free transcriptomic deconvolution highlights the importance of biological validation in astrocytes across Alzheimer’s disease

A comparative framework evaluating two complementary unsupervised approaches, CDSeq and DECODER, to reconstruct astrocyte-associated transcriptomic profiles from human hippocampal samples spanning control, mild cognitive impairment, and AD stages establishes a reproducible strategy for evaluating deconvolution methods...

Laura Rodríguez-Millan, Andrea Angarita-Rodríguez, Viviana Vargas-López et al. · 0 citations

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