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Author

Andrea Auditore

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Open access Oct 2026

CDK2/9 blockade remodels chromatin and drives phenotypic plasticity in glioblastoma organoids

Glioblastoma (GBM) remains a highly lethal brain tumor with limited therapeutic options and pervasive resistance to standard treatments. Cyclin-dependent kinases (CDKs), key regulators of cell cycle progression and transcription, are frequently dysregulated in GBM and contribute to tumor pathogenesis. We employed a ran...

P. Kaps, A. Hieltscher, Andrea Auditore et al. · 0 citations

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