Recurrence After Resection of Colorectal Liver Metastases and Its Impact on Survival: A Multistate Model-Based, Multi-institutional Observational Cohort Study.
BACKGROUND Conventional survival analyses cannot fully account for recurrence as an intermediate event that dynamically influences subsequent mortality. Multistate models (MSMs) enable explicit modeling of transitions between clinically relevant disease states; however, their application among patients undergoing resec...