Open access
Aug 2026
Inference of lineage hierarchies, growth, and drug response mechanisms in cancer cell populations without tracking.
Lineage hierarchies and plasticity regulate development and tissue homeostasis, while diverted lineage dynamics and aberrant phenotypic plasticity are among the causes of incomplete drug response and resistance in cancer. Knowing the dynamics of phenotypically heterogeneous populations is therefore central to understan...
Andrea Piras, F. Galvagno, Letizia Pizzini et al.
· Cell Reports Methods · 0 citations