Open access
Aug 2026
Oligodendrocyte dysfunction in human age-related cognitive decline.
Cognitive decline in aging impacts quality of life, for which therapeutic interventions are lacking. Why some individuals experience more severe cognitive decline with aging is unclear. Here we uncover a role for the brain's myelin-forming cells-oligodendrocytes-in explaining this variance. By investigating neuropathol...
Georgina A. Craig, Emeric Merour, L. Seeker et al.
· Nature Medicine · 0 citations