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Author

Andrea J. Darzi

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Open access Oct 2026

Addressing Limited Evidence in Guideline Development.

BACKGROUND Evidence-based guidelines are essential to optimize healthcare decision-making, yet in contexts such as rare diseases, emerging conditions, or specific subpopulations, direct evidence to estimate the magnitude of intervention effects may be minimal or absent. In these situations, guideline panels must formul...

Andrea J. Darzi, Emily Sirotich, S. Chowdhury et al. · 0 citations
Review Aug 2026

Instruments for measuring cultural and social environment well-being among Veterans: A systematic review

Introduction: The transition from military service to civilian life can affect Veterans’ well-being. The Veterans Affairs Canada cultural and social environment (CSE) domain reflects society’s dominant values, beliefs, and attitudes toward Veterans that influence their post-service well-being, including public perce...

G. Bravo-Soto, K. Torabiardakani, Daniela Montalva-Romero et al. · 0 citations
Review Open access Jul 2026

Surgical Management in Patients With Drug-Resistant Epilepsy: A Summary of Four Systematic Reviews and Meta-Analyses

In DR-MTLE, moderate-certainty evidence showed that anterior temporal lobectomy (ATL), compared with medical therapy, probably increases seizure freedom and improves QoL, and moderate-certainty evidence supports ATL in selected patients with DR-MTLE.

Y. Roldan, Barbara C. Jobst, Daniela Garcia-Aquino et al. · 0 citations

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