Author

Andrea J. Tenner

2 papers indexed here

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Review Open access Aug 2026

Complement-dependent phagocytosis in the clearance of various cellular targets.

It is concluded that complement is necessary for the optimal clearance of apoptotic cells, pathogens, myelin, cellular debris and weak synapses.

M. Blanter, Max L. B. Grönloh, P. E. Marques et al. · Protein & Cell · 0 citations

Open access Jul 2026

Young Adult Microglial Deletion of C1q Reduces Engulfment of Synapses and Partially Mitigates Cognitive Impairment in an Aggressive Alzheimer's Disease Mouse Model

C1q is a multifunctional protein, including its role as the initiating protein of the classical complement cascade. While classical pathway activation is involved in synaptic pruning during nervous system development, it also contributes to inflammation and cognitive decline in Alzheimer's disease (AD). Constitutive ge...

Tiffany J. Petrisko, Shu-Hui Chu, Angela Gomez-Arboledas et al. · Glia · 1 citation