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The Neuroprotective Effect of Cdc42 Inhibition in the G93A Mutant hSOD1 Mouse Model of ALS
It is suggested that Cdc42 inhibition can preserve neuromuscular structure and motor function in ALS, even in the absence of prolonged survival, and Cdc42 is identified as a novel contributor to ALS pathogenesis and a promising therapeutic target for slowing functional decline.
Andrea Koly
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