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Author

Andreas Schlosser

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Open access Oct 2026

Robust ORF Deconvolution from Multiple Ribo-seq Datasets with Group LASSO Penalty

Ribo-seq has provided compelling evidence that there are many translated but unannotated ORFs. Despite a growing body of peptidomic support for cryptic ORFs, the computational discovery of weakly translated, short and mutually overlapping ORFs has remained a major bottleneck. Here we introduce PRICE 2, a method designe...

Kilian Maidhof, Andreas Schlosser, Florian Erhard · 0 citations
Open access Jul 2026

The CRISPR/Cas-associated scaRNA modulates efeUOB expression and stress responses in Neisseria meningitidis

Abstract Neisseria meningitidis is a human-adapted commensal pathogen that must continuously balance nutrient acquisition with stress tolerance. Here, we identify a type II-C CRISPR/Cas-associated small RNA (scaRNA) as a posttranscriptional regulator of the efeUOB operon and oxidative stress responses. Using in vitro R...

Denise Pytlik, Milan Gerovac, Thorsten Bischler et al. · 0 citations

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