Andrei Segal

Chemical transfection reagents induce intracellular Ca2+ signals in TRPA1-expressing cells

Transient receptor potential ankyrin 1 (TRPA1) is a polymodal sensory ion channel whose activity is influenced not only by chemical ligands but also by the physical properties of the plasma membrane. This raises the possibility that membrane-active compounds used routinely in cell biology may alter TRPA1 function. We i...