Author

Andrés F Bedoya-López

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Open access Sep 2026

Primary Tumor Epigenetic and Transcriptomic Alterations Associated with Nodal Burden and Metastatic Risk in ER+/HER2− Breast Cancer

De-escalation of axillary surgery has resulted in the loss of pathologic nodal information, yet the extent of lymph node involvement remains an important determinant of treatment decisions in estrogen receptor-positive (ER+)/HER2− disease. We examined whether primary tumors differed molecularly according to the extent...

Sandra Íñiguez-Muñoz, Andrés F. Bedoya-López, Miquel Ensenyat-Mendez et al. · International Journal of Mol... · 0 citations

Open access Jul 2026

DNA methylation reprogramming of gene regulatory elements is associated with lung metastasis in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is a major cause of cancer mortality, with distant metastases, particularly to the lungs, presenting a significant clinical challenge. While epigenetic mechanisms like DNA methylation (DNAm) are known to influence TNBC progression, their association with lung metastasis remains unde...

Andrés F Bedoya-López, Sandra Íñiguez-Muñoz, Javier I. J. Orozco et al. · Communications Biology · 0 citations