Andrew E. Worthy

Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex

Fast-conducting Aβ slowly adapting type I low threshold mechanoreceptors (SAI-LTMRs) and Aβ rapidly adapting type I (RAI-) LTMRs are critical for discriminative touch from glabrous skin. Recent studies used mouse genetic loss-of-function and optogenetic gain-of-function manipulations to determine that signals from thes...