Steric stabilizers inhibit or enhance enzymatic digestion depending on the internal nanostructure of lipid nanoparticles
Lipidic nanoparticles (LNPs), including liposomes and cubosomes, are widely employed drug delivery systems owing to their biocompatibility and capacity for stimuli-responsive ‘smart’ drug release. Steric stabilizers, including DSPE-PEG-2000 and Pluronic F127, are commonly used to stabilize LNPs by creating an effecti...