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Author

Andrew L. Lemmex

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Open access Aug 2026

Aerolysin enables modular, non-genetic functionalization of living cell surfaces

It is shown that a non-cytotoxic, monomeric aerolysin mutant retains high-affinity and GPI-AP-dependent cell binding when genetically fused to diverse protein cargos and a DNA hairpin sensor is developed that converts cell-surface nuclease activity into a fluorescent signal and distinguishes cells with different levels...

Andrew L. Lemmex, M. Pawlak, Wendy R. Gordon · 0 citations
Open access Sep 2026

HUH-Enabled Programmable Antibody-DNA Conjugates for Profiling Receptor- Specific Cellular Mechanics

A modular antibody-to-nucleic-acid interface is established that expands DNA-based tension sensing beyond a restricted set of ligands and enables quantitative, multidimensional profiling of receptor-specific mechanical behavior across heterogeneous cell populations.

M. Pawlak, Lidia K. Limón, Andrew M. Baldys et al. · 0 citations

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