Open access
Sep 2026
Phage-assisted continuous evolution of enzymes for noncanonical tyrosine biosynthesis
It is shown that phage-assisted evolution can be used to rapidly optimize enzymes for the synthesis of noncanonical tyrosine derivatives in Escherichia coli and this platform provides a powerful approach for the rapid engineering of ncAA synthases amenable to use in cells.
James S. Andon, Abhijit Behera, Debashrito Deb et al.
· Proceedings of the National... · 0 citations