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Oct 2026

Targeted Intracellular Hydrogen Sulfide Delivery to Inflammatory Macrophages Reprograms Polarization and Mitigates Oxidative Stress in Osteoarthritis.

Osteoarthritis (OA) progression is driven by a chronic inflammatory microenvironment involving aberrant macrophage polarization and oxidative stress. Although the endogenous gasotransmitter hydrogen sulfide (H2S) possesses potent anti-inflammatory and antioxidant properties, its therapeutic application is hindered by r...

Zhen Zhang, Lei Yan, Cheng-Yu Wei et al. · 0 citations

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