SpikeSSL: A Universal Spike Inference Framework with Dynamics-Informed State-Space Layers
Two-photon calcium imaging is a standard tool for recording large neural populations in vivo, yet inferring spikes accurately across the growing diversity of calcium indicators remains an open problem. Existing supervised methods achieve reasonable in-domain accuracy but generalize poorly to unseen indicators, because...
Cheng-Hao Yue, Si-Ming Xing, Shu-Ran Liu et al.
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