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Author

Angela Marseglia

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2 papers indexed here

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Open access Jul 2026

Unveiling the molecular basis of Pleurocybella porrigens lectin (PPL)-glycan recognition by NMR and X-ray crystallography.

The structural basis of Gal/GalNAc selectivity in PPL is clarified and the broader utility of ricin-B-like lectins as probes for biologically and clinically relevant O-glycan epitopes is supported, highlighting the complementarity of NMR and X-ray crystallography for the integrated characterization of lectin-glycan int...

Angela Marseglia, Gabriella Tito, G. Ferraro et al. · 0 citations
Open access Aug 2026

From structure to function: binding determinants of a miniaturised phage depolymerase and their immunological relevance in Klebsiella pneumoniae capsule degradation.

This study provides a comprehensive NMR and mutational analysis to characterise the mechanism of action of a miniaturised depolymerase, here mKP34gp57, targeting the clinically relevant K63 CPS, and shows by NMR that mKP34gp57 hydrolyses CPS with high efficiency through an endoglycosidase-retaining mechanism.

Ferran Nieto-Fabregat, Mario Privitera, Angela Marseglia et al. · 1 citation

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