Author

Aniello Acampora

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Review Open access Aug 2026

PIK3CA in Cancer: Structure, Biology, Alterations, and Actionability

This review provides a comprehensive, updated, and comparative overview of PIK3CA biology, its molecular alterations across human cancers, their prognostic and therapeutic relevance, and the current development of treatments targeting the pathway activated by PIK3CA.

A. Ottaiano, C. Picone, M. Santorsola et al. · Cancers · 0 citations