Self-adaptive copper-enriched Prussian blue nanozymes for cascade ROS scavenging and neurofunctional recovery in cerebral ischemia-reperfusion injury.
Ischemic stroke (IS) and the subsequent reperfusion induce severe oxidative stress and mitochondrial dysfunction through the excessive generation of reactive oxygen species (ROS). However, most existing therapeutic strategies target only a single pathological pathway, thereby limiting their therapeutic efficacy. Herein...