Review
Open access
Sep 2026
B7-H3-mediated immune regulation in cancer: biological functions and therapeutic opportunities
B7-H3 (CD276), a member of the B7 family of immunoregulatory ligands, has emerged as an important molecule at the intersection of tumor biology and cancer immunology. Although initially identified as a regulator of T-cell responses, accumulating evidence supports its predominantly immunosuppressive role. B7-H3 is highl...
Shreya Shreshtha, Lasini Kaluarachchige, Olivia A. Meyer et al.
· Frontiers in Pharmacology · 0 citations