Open access
Sep 2026
Cardiovascular Effects of Chronic GIPR and GLP-1R Agonism in Lean and Diet-Induced Obese Mice: Sex Differences and Dose-Dependent Remodeling.
Glucose‑dependent insulinotropic polypeptide (GIP) and glucagon‑like peptide‑1 (GLP‑1) regulate metabolism and are increasingly targeted in therapies for type 2 diabetes and obesity. Although GLP‑1 receptor agonists confer cardiovascular benefits, the cardiovascular effects of GIP receptor (GIPR) stimulation remain con...
Sevilay ŞahoŞlu Göktaş, Annelise Francisco, J. M. Duarte et al.
· American Journal of Physiolo... · 0 citations