Open access
Aug 2026
Synovial lining macrophages form during early postnatal life via fetal-derived CX3CR1+ cells and AQP1+ intermediates.
It is found that the lining is immature in fetal human and newborn mouse joints, and early postnatal life is a critical window for synovial lining maturation with implications for joint health and disease.
Marlene S. Magalhaes, B. Malengier-Devlies, Guillaume Seuzaret et al.
· Cell Reports · 0 citations