Author

Anna-Maria Dittrich

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Open access Oct 2026

Vanzacaftor/tezacaftor/deutivacaftor partially restores CFTR function of the L467F;F508del complex allele in primary nasal epithelial cells.

Highly effective CFTR modulator therapies have transformed the treatment of cystic fibrosis (CF). Elexacaftor/tezacaftor/ivacaftor (ETI) leads to restoration of CFTR-mediated chloride transport of around 40% of normal CFTR activity and results in substantial clinical benefits in people with CF and at least one F508del...

Jasmin Berger, A. Balázs, R. Dalferth et al. · Journal of Cystic Fibrosis · 0 citations

Open access Jul 2026

Increased high sensitivity C-reactive protein in more severe wheeze/asthma phenotypes in child- and adulthood in ALLIANCE

HsCRP was increased in adult asthmatics compared to HCs and was associated with several severity-related clinical characteristics, whereas ICS use in preschool wheezers was associated with lower hsCRP levels.

Lena Lagally, Lena Ullemeyer, J. Omony et al. · Respiratory Research · 0 citations