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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Annan S. I. Cook

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Open access Oct 2026

Mechanisms of intracellular pH gating and local anesthetic inhibition of the two-pore domain K+ channel TASK-2.

TWIK-related acid-sensitive K+ channel 2 (TASK-2) is a pH sensing two-pore K+ (K2P) channel that regulates respiration in brainstem neurons and systemic pH homeostasis in kidney. Despite its physiological importance and implication in disease, the molecular basis for intracellular gating and pharmacological inhibition...

Trevor A. Docter, B. Sorum, Bao-Bin Li et al. · 0 citations

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