Open access
Aug 2026
SpY-C: Supervised Learning of Phosphopeptide Sequence Constraints Enables Global Prediction of SH2 Domain Binding
SpY-C is used as a classifier to annotate the human phosphoproteome and individual experiments, to explore the consequences of using super-SH2 domain reagents for pY enrichment, and to analyze the effects of mutations in altering pY site function.
Alekhya Kandoor, Anny Carolline Silva Oliveira, K. Machida et al.
· bioRxiv · 1 citation