Author

Anthony N. Vomund

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Open access Sep 2026

Priming of CD8+ T cells by peripheral dendritic cells exacerbates tau-mediated neurodegeneration.

Alzheimer's disease and primary tauopathies are marked by changes in adaptive immunity, with increased brain CD8+ T cells correlating with tau pathology severity. However, how peripheral T cells get primed to enter the brain and contribute to tau-mediated neurodegeneration remains unclear. In different disease conditio...

Hao Hu, P. Lin, Carisa Zeng et al. · Nature Neuroscience · 0 citations

Open access Aug 2026

Personalized Neoantigen Vaccines Synergize with Immune Checkpoint Therapy and CD8-Targeted Cytokines to Control B-Cell Lymphoma

A framework for optimal personalized neoAg vaccination in B-lymphoma is defined and it is demonstrated that neoAg vaccines can safely synergize with CD8+ T cell-selective immunotherapies to prevent T-cell dysfunction and generate durable systemic anti-tumor immunity.

Yuang Song, E. Aladyeva, Ruan F. Vieira Medrano et al. · bioRxiv · 0 citations