We present Datamonkey 3, a browser-native implementation of the Datamonkey web platform for molecular evolutionary analysis. By utilizing WebAssembly to execute the HyPhy analysis engine on the client side, Datamonkey 3 removes the dependency on remote computational clusters for standard analyses. This architecture ens...
Steven Weaver, Ben Murrell, Anton Nekrutenko et al.· Frontiers in Bioinformatics· 0 citations
By bridging statistical phylogenetics with geometric representation learning, HyphAeon establishes comparative genomics as an interactive, high-throughput computational framework for evolutionary discovery.
Sergei L. Kosakovsky Pond, Steven Weaver, Danielle Callan et al.· bioRxiv· 0 citations
PRIME (PRoperty Informed Models of Evolution), a framework of codon-level maximum likelihood methods that explicitly model amino acid exchangeability as a function of physicochemical properties, provides a useful framework for characterizing the mechanistic drivers of protein diversity.
Hannah Kim, Konrad Scheffler, Anton Nekrutenko et al.· Molecular biology and evolut...· 0 citations
A rate-based stasis threshold is defined to identify evolutionary stasis anchors (ESAs)—sites where the upper bound on the evolutionary rate is statistically constrained relative to the background rate of the gene due to extreme purifying selection.
Sergei L. Kosakovsky Pond, Hannah Verdonk, Steven Weaver et al.· Genome Biology and Evolution· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
