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A. Sculean

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Review Open access Oct 2026

Ten years and beyond: Long-term dental implant survival, success, and biological health-A systematic review and meta-analysis.

OBJECTIVES To update dental implant failure and survival estimates beyond 10 years and examine how success definitions and biological outcomes affect interpretation of long-term performance. MATERIALS AND METHODS Randomized controlled trials, prospective cohorts, and retrospective cohorts with at least 10 years of fo...

V. Moraschini, Krisztina Mikulás, J. A. Shibli et al. · 0 citations
Review Open access Aug 2026

Periodontitis and metabolic dysfunction-associated steatotic liver disease.

OBJECTIVE Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive phenotypes, have eme...

R. S. de Molon, E. D. de Avila, D. da Silva Barbirato et al. · 1 citation
Open access Oct 2026

Periodontal Treatment Restores Gingival Crevicular Fluid and Serum Periostin Levels.

BACKGROUND AND AIM To investigate the effect of periodontal treatment on periodontal inflammation and periostin levels in patients with severe periodontitis. METHODS This study included two groups (periodontitis and periodontally healthy), each comprising 24 individuals. Periodontal clinical parameters were recorded,...

Aysegul Sarı, O. Ozcan, F. Kaçmaz et al. · 0 citations
Review Open access Aug 2026

Understanding extracellular vesicles in antiaging.

EVs represent promising therapeutic agents and biomarkers in aging biology, with the potential to regulate multiple hallmarks of aging concurrently, and should be prioritized for successful antiaging interventions.

Paras Ahmad, N. Estrin, A. Sculean et al. · 0 citations
Review Open access Aug 2026

Individualized healing significantly improves pink esthetics around immediate single implants: A systematic review and meta-analysis.

AIM This systematic review and meta-analysis aimed to compare soft and hard tissue outcomes of applying anatomic healing abutments (AHA) and provisional restorations (PR) versus cylindrical healing abutments (CHA) on immediately placed single implants. MATERIALS AND METHODS Four databases (PubMed, Embase, Cochrane, a...

Xinyi Qian, Boldizsár Vánkos, G. Agócs et al. · 0 citations
Open access Aug 2026

Smart Coatings Integrating Antimicrobial and Tissue-Remodeling Functions for Implant Interfaces.

The multifunctional coating provides sustained antimicrobial activity alongside immunomodulatory and pro-regenerative effects, supporting its potential to treat implant-related infections while enhancing peri-implant soft tissue remodeling.

Mariana Martins Guerreiro, Amanda Paino Santana, D. M. Cunha et al. · 0 citations

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