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Author

Antonio Marra

1 paper indexed here

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Review Sep 2026

Beyond poly(ADP-ribose) polymerase inhibition: emerging therapeutic strategies for germline BRCA1/2-mutated and PALB2-mutated breast cancers.

PURPOSE OF REVIEW Germline or somatic biallelic inactivation of BRCA1, BRCA2 and PALB2 genes define a clinically and biologically distinct subset of breast cancers characterized by homologous recombination deficiency (HRD) and sensitivity to PARP inhibitors. Despite regulatory approvals of olaparib and talazoparib for...

J. Etessami, L. Tori, M. Aconito et al. · 0 citations

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