Anugula Chandra Shekhar

De Novo Design of Novel Pks13 Inhibitors Rational Drug Design via Machine Learning-Guided Molecular Docking and QSAR Modelling for Mycobacterial Mycolic Acid Biosynthesis Inhibition

Tuberculosis remains one of the world's most significant infectious diseases, with approximately 10 million new cases annually. The polyketide synthase 13 (Pks13) enzyme, responsible for the final cyclopropanation step of mycolic acid biosynthesis, has remained understudied as an antituberculous drug target despite its...