Intact spatial learning in Fmr1–/y, Syngap1+/–, and Grin2b+/– rat models of neurodevelopmental disorders
FMR1, SYNGAP1, and GRIN2B gene mutations Q8 are known causes of mild to severe intellectual disability (ID) in humans, with affected individuals frequently co-diagnosed with autism spectrum disorder (ASD). These three genes influence molecular mechanisms underlying synaptic plasticity, and thus spatial memory behav...