Anupam Mukherjee

Development and clinical validation of a colorimetric isothermal assay for rapid detection of monkeypox virus

Background Monkeypox virus has re-emerged as a global public health concern, highlighting the need for rapid, accurate, and accessible diagnostic tools. Real-time quantitative polymerase chain reaction is the reference standard for MPXV detection; however, its reliance on specialized infrastructure limits use in decent...

A novel synergistic phycobiliprotein combination against HIV-1 shows potent antiviral activity

Human immunodeficiency virus type 1 (HIV-1) remains a major global public health challenge due to lifelong persistence, latency, and the emergence of drug resistance. Natural bioactive compounds are increasingly being explored as alternative or adjunct antiviral strategies. In this study, we evaluated the antiviral eff...

Structure based discovery of VMP-7 as a promising GlgE targeting lead against Mycobacterium tuberculosis

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), remains a major global health challenge, necessitating the identification of novel drug targets with high specificity and therapeutic potential. Maltosyltransferase (GlgE) is a critical enzyme in the biosynthesis of cytosolic α-glucan, a key component requ...

Clove Oil-based Nanoemulsion Co-loaded With Saquinavir, Ritonavir and Acyclovir for Enhanced Oral Pharmacokinetics and Brain Exposure in Herpes Simplex Encephalitis and NeuroAIDS