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Anusha Iyengar

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Open access Aug 2026

Hyperactive intestinal proteolysis underlies smn-1 mutant phenotypes

How the ubiquitously-expressed SMN-1 protein is required in a single tissue to avoid degenerative defects caused by hyperactive proteasome activity is revealed, contributing to the understanding of how mutations in ubiquitously-expressed genes can cause highly cell-specific pathologies.

Anusha Iyengar, Lindsey Philips, Adam D. Norris · 0 citations

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