Anwita Chattopadhyay

Stereoselective Synthesis of Aminals Through Enzyme-Catalyzed Intermolecular C(sp3)-H Amidation of Azacycles.

Stereogenic aminals are widespread in natural products, pharmaceuticals, and biologically active compounds, including important classes of antibiotics. Methodologies for asymmetric synthesis of aminals are therefore highly desirable, yet they remain scarce and mostly rely on C─N bond formation at functionalized carbon...