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Author

Ao Guo

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Open access Sep 2026

In vivo CRISPR Screening Reveals LBR as a Regulator of CD8+ T Cell Fate Decision.

CD8+ T cells play an important role in anti-infection and anti-tumor immunity. Metabolic reprogramming has emerged as a critical regulator of T cell function, yet the roles of specific cholesterol-associated proteins during T cell fate trajectories remain unclear. Here, using an in vivo CRISPR screen in CD8+ T cells du...

Qi-Ying Zhang, Shu-Ya Chang, Sheng-Li Zhao et al. · 0 citations

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