Author

Apoorva Chouksey

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Open access Aug 2026

Polymer-specific nanoplastics trigger oxidative stress, inflammatory activation, and mitoepigenetic remodeling: in vitro and in silico evidence for MT-ND6-mediated mitochondrial complex I perturbation

Introduction Recent studies have detected nanoplastics (NPs) in human tissues and biological fluids, raising concerns regarding their potential effects on cellular homeostasis. Nevertheless, their effects on mitochondrial regulation and mitoepigenetic processes remain poorly understood. This work aimed to study the pol...

P. K. Mishra, Aneha K. Rajan, Apoorva Chouksey et al. · Frontiers in Toxicology · 0 citations

Open access Aug 2026

Comparative Analysis of Ultrafine Particulate Matter, Black Carbon, and Polystyrene Nanoplastics Identifies Mitochondrial Stress Adaptation as a Conserved Mechanism of Immunotoxicity

It is found that mitochondrial stress response is a common mechanism underlying the toxicity of chemically different nanoparticles and have also revealed particle-specific stress-response dynamics responsible for the degree and persistence of cellular damage.

P. K. Mishra, Apoorva Chouksey, Aneha K. Rajan et al. · bioRxiv · 0 citations