Open access
Aug 2026
Functional phosphoproteomic analysis of SMG1 in nonsense-mediated mRNA decay and DNA damage repair in cancer
Findings identify SMG1 as a central phosphorylation hub integrating nonsense-mediated mRNA decay with genome maintenance pathways and provide the first systematic phosphosite-centric framework for understanding its regulation.
Apoorva Pai, Leona Dcunha, Athira Perunelly Gopalakrishnan et al.
· Frontiers in Systems Biology · 0 citations