Predictive accuracy of peptide–target interaction models in drug discovery: a systematic review and meta-analysis
Background Peptides represent promising therapeutic agents due to their high specificity, biocompatibility, and capacity to modulate protein–protein interactions. However, the field faces critical challenges: inconsistent evaluation metrics, heterogeneous datasets, and poor reproducibility, which together undermine obj...
William Waldock, Ahmad Guni, Ara Darzi et al.
· Frontiers in Drug Discovery · 0 citations