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Open access Sep 2026

Pre-hospital time and risk of perforation in patients with acute appendicitis in 112 countries (AlliGatOr): an international, prospective, observational cohort study.

BACKGROUND Acute appendicitis is the most common surgical emergency worldwide. Concern that delayed treatment might increase perforation can lead to unnecessary surgery and high rates of negative appendicectomy, where a normal, non-inflamed appendix is removed. However, whether perforation is related to pre-hospital ti...

T. Anyomih, A. Aregawi, J. A. Calvache et al. · 0 citations
Review Open access Sep 2026

Global challenges and perspectives in acute and emergency general surgery in low and middle-income countries: a scoping review

Abstract Background Acute and emergency general surgery in low and middle-income countries (LMICs) faces critical disparities. Despite global and regional initiatives, surgical inequities persist due to fragile healthcare infrastructure, workforce shortages and insufficient policy integration. This study explores the s...

M. Hindawi, Arda Isik, Fausto Rosa et al. · 0 citations

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